Not an M.D. either but I will try to give some answers.
For the first situation, I would say no one was right. If it was injected in the bloodstream (it is not that common unless there is already a KT) you probably would rapidly experience a mild hypoglycemia although not something dangerous and in a few hours at most would be ok, or you could drink a can of coca or similar and more than offset what you injected.
Yakk wrote:I don't know how many doses he injected himself with, but I assume the usual amount. And I'm not aware that type 1 diabetics are particularly worse at dealing with insulin spikes than normal folks?
The usual amount might change a lot if he follows a functional insulin treatment. Also, sometimes shallow hypoglycemia can be more debilitating.
It depends on the spike, natural spikes are still quite different from those used in diabetes so the comparison isn't easy. I looked at the study linked by qetzal and it looks like there is a difference from what I know about how type 1 diabetics reacts (they would have had a lower glycemia).
quetzal, there were tests to make the patient absorb it in a dissociated form, their results were not that great either.
Yggdrasil wrote:If insulin could be taken into the bloodstream via oral ingestion, do you think type I diabetics would be taking insulin injections rather than just using insulin pills?
It is too early to say but the advantage of injections at this time is that its effects are (very) well known.
iop wrote:No. Injecting means that you have to reduce the number of insulin uptakes, which makes it much harder to get the right insulin level.
Not necessarily, insulin pumps or various types of insulin + functional insulin treatment have sufficient observance.
iop wrote:Injecting means that you need to carry equipment with you.
Depends on your lifestyle, you can easily have a set at home and another at work. Insulin pumps reduce that problem too.
iop wrote:Seriously, if you invent an insulin pill, you are rich.
Certainly, however that will only be a first step.
ArgonV wrote:Are you sure? Don't they have does pen-like syringes that can be set to inject the needed dose? That's what the device of a former classmate of mine looked like anyway. When she showed me how to do it, in case of hyperglycaemia, she told me to just prick one end in her and press the other end. She might've had something out of the ordinary though.
Unless it is something I never heard of, she was probably doing it wrong. And, anyway, these pens still hurt and have potentially dangerous long term consequencies.
Hyperglycaemia can require an amount of insulin varying from a few units to tens of units. There are a number of injection sites but in case of emergency that is not a real problem. However, if she can't do it herself, she should be sent to the hospital ASAP.
ArgonV wrote:Also, isn't the timing real easy to figure out? The same girl had to have breakfast, lunch and dinner at approximately the same time every day (she had a leeway of about half an hour), so she didn't have any problems with her blood sugar.
It is hard to tell without knowing what she used, but regular schedules are generally a good idea.
sgt york wrote:
ArgonV wrote:And if you really want to get rich, invent a subdermal insulin-pump
, something like that. Money will change hands.
I think he was talking about artificial pancreas.